Vaccine efficacy tended to be higher when the interval between doses was longer. WHO does not recommend discontinuing breastfeeding because of vaccination. 57 0 obj <> endobj xref In the meantime, we must maintain and strengthen public health and social measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation. 0000009792 00000 n LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. 0000132021 00000 n Keep vials in outer carton to protect from light. 841 0 obj <>/Filter/FlateDecode/ID[<361FB7422BB7104D9CF07822BCE868F6>]/Index[818 53]/Info 817 0 R/Length 108/Prev 89098/Root 819 0 R/Size 871/Type/XRef/W[1 2 1]>>stream Preliminary findings highlight the urgent need for a coordinated approach for surveillance and evaluation of variants and their potential impact on vaccine effectiveness. He tells Elisabeth Mahase how the Oxford vaccine came to be, how dosing was worked out, and whether it will stand up to the new variants. You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. It can be life-threatening; If you have ever fainted following any needle injection; If you currently have a severe infection with a high temperature (over 38C). Contents of the pack and other information 1. A court in Belgium . This webpage was updated on 16 March 2022 to reflect the latest guidance and ensure consistency of information and formatting. By reporting side effects you can help provide more information on the safety of this vaccine. 0000001096 00000 n 10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. 0000004762 00000 n Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 90.3% were aged 18 to 64 years and 9.7% were 65 years of age or older. Neutralising activity against SARS-CoV-2 (as assessed by the MNA80 assay) was seen in 91% of participants one month after vaccination and in 100% of participants who received a second dose. Use all vaccine in the vial within 6 hours after first puncture. Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. 0000004537 00000 n The last nine ingredients on the list are called 'excipients.' hbbd```b``3@$1dYL`)`5w. 2020 has been a difficult year for all, but has seen 58 vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) be developed and in clinical trials,1 with some vaccines reportedly having more than 90% efficacy against COVID-19 in clinical trials. 548 0 obj <> endobj This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. hbbd``b` $HpXAv DL) Available for Android and iOS devices. Consumer Information. In line with the WHO Prioritization Roadmapand and the WHO Values Framework older adults, Some cases were life-threatening or had a fatal outcome. 0000132090 00000 n If you miss an appointment for your second injection of COVID-19 Vaccine AstraZeneca Article number: 33474. SR-3086-GB-0003 AstraZeneca UK Ltd, Medical Information Department Page 1 of 2 Last Updated January 7, 2021 Return to Index COVID-19 Vaccine AstraZeneca (ChAdOx1 S [recombinant]) - General Ingredients AstraZeneca is providing you with this material as an information service and professional courtesy. endstream endobj startxref <>stream Some people have reported a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache (including migraine-like headaches), nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two. Vaccine AstraZeneca and those who received control. 0000098057 00000 n RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H 0000004413 00000 n 0000083589 00000 n COVID-19 Vaccine AstraZeneca stimulates the bodys natural defences (immune system). The AstraZeneca vaccine does contain polysorbate. %%EOF % COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). After COVID-19 immunization, it takes a few weeks for the body to build immunity so that you are protected from the virus. This phase also helps researchers understand how well a vaccine works over a longer time frame and how safe it is for the population. Dont worry we wont send you spam or share your email address with anyone. a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. Your doctor, pharmacist or nurse will discuss with you whether you can be given the vaccine. Ingredients in the Pfizer-BioNTech Comirnaty COVID-19 vaccine. <>/Metadata 30 0 R>> Can they overcome their checkered past? This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . endstream endobj 75 0 obj <> stream Like any vaccine, the COVID-19 vaccines do come with potential side effects. 803 0 obj <>/Filter/FlateDecode/ID[<2F70D35E7B8A59458B52A8ED8203A71C><24F7C9D4F005C249BEA4CA3B57A534AF>]/Index[779 189]/Info 778 0 R/Length 129/Prev 229930/Root 780 0 R/Size 968/Type/XRef/W[1 3 1]>>stream To get around the problem, scientists used virus from a chimpanzee to ensure people would not have any natural immunity to it. impact. 346 65 Vaccines, by Vaccine In addition to weakened or killed disease antigens (such as weakened, killed, or parts of viruses or bacteria), vaccines contain very small amounts of other ingredients - excipients. It uses a chimpanzee adenovirus to carry spike proteins from the . Draw up the vaccine dose at the time of administration, pre-loading of syringes is not recommended. 0000014217 00000 n Solution for injection. Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. It's only capable of delivering the DNA," he said. %PDF-1.7 information about the risks of COVID-19 in pregnancy, the likely benefits of vaccination in the local epidemiological context, and the current limitations of safety data in pregnant women. Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. Unit dose strength (s) > 0.7 1011 vp/mL. The AstraZeneca vaccine is made up of a number of ingredients, including an active ingredient called an 'antigen' and several other non-active ingredients called 'excipients.' 779 0 obj <> endobj COVID-19 Vaccine AstraZeneca contains sodium and alcohol). The Council for International Organizations of Medical Sciences classifies rates of adverse events or medicines and vaccines as follows: The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about x]n@FwezA"+q*z B-csD"%;>3a,7Mg>;M1crUukGavi%. hb``g``oc`c` @1v=k}u F'SUNZ On his way to a meeting to present . 6`CA$'i$W30120ma`$p@ J 0000008310 00000 n 0000025064 00000 n Moderna bivalent COVID-19 vaccine. 569 0 obj <>/Filter/FlateDecode/ID[<422DFA914F61AD45909E39C193482A39>]/Index[548 34]/Info 547 0 R/Length 105/Prev 177378/Root 549 0 R/Size 582/Type/XRef/W[1 3 1]>>stream 0000002960 00000 n However, maintaining a homologous schedule is still acceptable. This is not enough to cause any noticeable effects. 53 0 obj vaccination series and are at higher risk of severe COVID-19 disease. are no data yet for Omicron. xVN@}W#E{I HTJB+!`)m;:KQyX99se If you get any side effects, talk to your doctor, pharmacist or nurse. LYpeP4 &=C&CBzLL3y20gah!A '1>ederj4+e@Zg Rc`TaPa`2R6r G2p T This will help to protect you against COVID-19 in the future. endstream endobj 76 0 obj <> stream That way, when a person is exposed to COVID-19, its immune system will recognize the part of the virus that has those spike proteins and will know how to how to fight it. 0000006617 00000 n Any unused vaccine or waste material should be disposed of in accordance with local requirements. 0000085176 00000 n x P^0^N&8:Cssfo"E$hq(#^G78@ The manufacturer URL for this document will be provided once that is available. CLS is a serious, potentially fatal condition causing fluid leakage from small blood vessels (capillaries) resulting in rapid swelling of the arms and legs, sudden weight gain and feeling faint (low blood pressure). }wfydUj_mr\]]s=']O_Od>MdD.PHTpo Information about the Moderna bivalent coronavirus vaccine, including vaccine ingredients, is available: %PDF-1.7 % %%EOF %PDF-1.6 % 0000012641 00000 n /ID [<46442D36362D36432D33412D43412D36>] CoronaVac is an inactivated vaccine. You have rejected additional cookies. . (see section 2. The Astra-Zeneca vaccine can be offered to people who have had COVID-19 in the past. If you have a previous diagnosis of capillary leak syndrome (a condition causing fluid leakage from small blood vessels). Dosage level (s) 5 1010 vp (nominal). The AstraZeneca vaccine remains a safe and effective choice to protect against COVID-19, and will protect against severe outcomes from getting infected with COVID-19, including illness, hospitalization and death. 0000098749 00000 n No substantive data are available related to impact of the vaccine on transmission or viral shedding. AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. You may access the guidance document here. 870 0 obj <>stream Wait until any effects of the vaccine have worn off before you drive or use machines. Over the years, researchers have considered adenoviruses useful delivery systems for vaccines and gene therapies. 0000009880 00000 n This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. 0000001732 00000 n Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. WHO will continue to review these rare reports of GBS and to work closely with national regulators to manage potential risks. The Oxford-AstraZeneca vaccine contains no pork products or by-products. serious nerve inflammation, which may cause paralysis and difficulty breathing (Guillain-Barr 0000008003 00000 n Well send you a link to a feedback form. What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. Pack sizes (not all pack sizes may be marketed): MedImmune UK Ltd What is the evidence for use in older age groups? When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. %%EOF 0000011249 00000 n request information about a specific topic, United Kingdom Medicines & Healthcare products Regulatory Agency, University of Oxford Vaccine Knowledge Project, United States Centers for Disease Control and Prevention, A weakened adenovirus, which delivers the the COVID-19 spike glycoprotein (this is the active ingredient; also called the 'antigen'), L-histidine hydrochloride monohydrate (amino acid), Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial (, A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity (, Adenoviral vectors are the new COVID-19 vaccine front-runners. 0000088968 00000 n The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. Discard the vial and do not combine residual vaccine from multiple vials. Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. *Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. O'`` r/ RV"Lj~=n%8w?C * Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Very low levels of blood platelets (immune thrombocytopenia), that can be associated with bleeding, have been reported very rarely, usually within the first four weeks following vaccination with COVID-19 Vaccine AstraZeneca. Keep this leaflet. If you feel unwell after vaccination, do not drive or use machines. /Info 87 0 R This type of vaccine technology has been tested for many other diseases such as influenza (flu) and middle east respiratory . 0000004761 00000 n xref The AstraZeneca vaccine is based on an adenovirus that circulates in chimpanzees . 0000006047 00000 n hbbd```b``5d4d""A$a0DEE4$U0 Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. This Oxford-AstraZeneca vaccine uses the ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10 years. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. Spills should be disinfected using agents with activity against adenovirus. 2. Once approved, the drugmaker will work with national governments and international health organizations to monitor vaccine recipients for potential side effects from the vaccine that were not seen in clinical trials (this is called surveillance). The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has issued interim recommendations for use of the Oxford/AstraZeneca COVID-19 vaccine (ChAdOx1-S [recombinant] vaccine). Active ingredient: 0000023338 00000 n 581 0 obj <>stream 0000102371 00000 n Very rare cases of capillary leak syndrome (CLS) have been reported following vaccination with COVID-19 Vaccine AstraZeneca. 0000106271 00000 n syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). 0000002028 00000 n These ingredients range from forms of salt that help preserve the vaccine to water that dilutes it into the right concentration. Vaxzevria is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 18 years and older. If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] 57 40 November 2020 - Trial data dispute. A: None of the authorized COVID-19 vaccines in use in Canada contain the live virus that causes COVID-19. You can change your cookie settings at any time. Talk to the healthcare provider if you have questions. If you are allergic to any of the active substances or any of the other ingredients listed in section 6. tenderness, pain, warmth, itching or bruising where the injection is given, swelling, redness or a lump at the injection site, flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills, sleepiness, feeling dizzy, or deep unresponsiveness and inactivity, excessive sweating, itchy skin, rash or hives. In countries with ongoing 0000082376 00000 n After the first dose is withdrawn, the vaccine should be used as soon as practically possible and within 6 hours. The COVID-19 vaccines currently approved for use in the UK are: Moderna (Spikevax) Pfizer/BioNTech (Comirnaty) Novavax (Nuvaxovid) AstraZeneca (Oxford) (not available) Janssen (Johnson & Johnson) (not available) Valneva (Valneva) (not available) Which vaccine will I get? 0000054470 00000 n Vaccines are generally very safe and their study involves a rigorous process. This means that a COVID-19 vaccine cannot make you sick with COVID-19. 0000097788 00000 n Some of the side effects listed in section 4 may temporarily reduce your ability to drive and use machines. If you forget to go back at the scheduled time, ask your doctor, pharmacist or nurse for advice. Most people have been exposed to them in their lives. "It can't give you an infection. /Root 55 0 R AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. 0000009594 00000 n How COVID-19 Vaccine AstraZeneca is given 4. The average age of those who have experienced severe allergic reactions so far is . AstraZeneca is a member of Covax, a global initiative aiming to distribute two billion vaccine doses to 92 low- and middle-income countries at no more than $3 a dose. hb```Y@(&(fL(aW$Xz$7 5. . After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. Neither Pfizer nor Moderna . Treatment for: Prevention of COVID-19. The Anglo-Swedish firm has . Moderna; you may take J&J vaccine You should not receive the vaccine if: Talk to your medical provider before getting this vaccine to review your medical conditions, including allergies to any of the vaccine ingredients as listed at right, or if you have had severe reactions to other vaccines in the past If you have questions or concerns: 1. 0000015824 00000 n We use some essential cookies to make this website work. "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. it contains the weakened adenovirus encoding the SARS CoV 2 Spike glycoprotein, as well as the following excipients: L-histidine L-histidine hydrochloride monohydrate magnesium chloride hexahydrate. The majority of these cases occurred within the first 3 weeks following vaccination but some have also been reported after this period. It is important to remember the benefits of vaccination to give protection against COVID-19 still outweigh any potential risks. >> Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Countries should It is a proven, safe and relatively old approach. COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). Success! Safety data sheet. The Oxford-AstraZeneca vaccine is cheaper and easier to transport and store than some of the other vaccines approved for use to date and as such, was going to play a key part in combating the . << /Linearized 1 /L 149707 /H [ 2229 301 ] /O 59 /E 79897 /N 11 /T 149221 >> py]IioB^;+q/u_q^okl@ 0s7(-e?rbBS\Lg!-,p77cicd@&( 0000010323 00000 n The Oxford-AstraZeneca vaccine contains no common food allergens such as milk, wheat, egg, peanuts, tree nuts, or shellfish, or their by-products. Once this enters the body, it tells your cells to make copies of the spike protein. endobj Component. Vaccine ingredients; Nucleic acid and viral vector vaccines explained . Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take, any other medicines or vaccines. endstream endobj 549 0 obj <. 0000003223 00000 n It is not yet known how long you will be protected for. 0000006565 00000 n hb```(1A;B% AZD1222 works by using a viral vector (ChAdOx1 - chimpanzee adenovirus Oxford 1) based on a weakened version of a common cold (adenovirus) virus that contains the genetic material of the SARS-CoV-2 virus spike protein. endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. As with any vaccine, the 2-dose vaccination course of COVID-19 Vaccine AstraZeneca may not fully protect all those who receive it. Epub 2020 Dec 8. We also use cookies set by other sites to help us deliver content from their services. The solution is colourless to slightly brown, clear to slightly opaque. However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). We wont send you spam or share your email address with anyone pack of vials... N Moderna bivalent COVID-19 vaccine AstraZeneca is given as an injection of COVID-19 vaccine.! Endobj 75 0 obj vaccination series and are at higher risk of COVID-19... Reflect the latest guidance and ensure consistency of information and formatting W30120ma ` HpXAv! These rare reports of GBS and to work closely with national regulators to potential! Nine ingredients on the safety of this vaccine years and astrazeneca vaccine ingredients pdf by the Jenner Institute over years. Over the years, researchers have considered adenoviruses useful delivery systems for vaccines and gene therapies vial 5... 12 weeks for any information about this medicine, please contact: leaflet... Of 0.5 ml into a muscle ( usually in the past ` Y @ ( & ( (! Cells then recognise the spike protein you whether you can be offered to people who have had COVID-19 in upper. ( fL ( aW $ Xz $ 7 5. replication-deficient chimpanzee adenovirus to spike. `` b ` $ p @ J 0000008310 00000 n Keep vials in outer to. ( 5 ml ) with an interval of 8 to 12 weeks this is not recommended the... Be protected for two doses given intramuscularly ( 0.5ml each ) with rubber stopper and aluminium overseal in pack... Will continue to review these rare reports of GBS and to work closely with national to... 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Revised on 26/01/2022 > /Metadata 30 0 R AZD1222 ( formerly ChAdOx1 nCoV-19 ) is an investigational vaccine against in... Build immunity so that you are taking, have recently taken or might take, any medicines... Means that a COVID-19 vaccine AstraZeneca is given as an injection of COVID-19 of. That a COVID-19 vaccine authorized COVID-19 vaccines in use in Canada contain the live virus that COVID-19... Years and older was last revised on 26/01/2022 webpage was updated on 16 2022... Interval of 8 to 12 weeks also use cookies set by other sites to us. Dilutes it into the right concentration the years, researchers have considered adenoviruses useful delivery systems for vaccines gene! Covid-19 disease capable of delivering the DNA, & quot ; it can & # x27 ; only... But Some have also been reported after this period ; it can & # x27 ; t you. Had COVID-19 in the vial within 6 hours after first puncture to immunity! ` b `` 3 @ $ 1dYL ` ) ` 5w syringes is not recommended each ) rubber! 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Vaxzevria is a vaccine for preventing coronavirus disease 2019 ( COVID-19 ) in aged! Replication-Deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 spike glycoprotein by reporting side effects listed in section 4 temporarily! Unwell after vaccination, do not combine residual vaccine from multiple vials `` oc ` c `  @ }... Medicine, please contact: this leaflet was last revised on 26/01/2022 vaccine! Protected for you drive or use machines have experienced severe allergic reactions so far is, Some cases were or. Vials in outer carton to protect from light Xz $ 7 5. multiple vials the vaccine have worn off you! Reactions so far is in the vial and do not combine residual vaccine from vials. Dose multidose vial ( 5 ml ) with an interval of 8 to 12.. ) in people aged 18 years and older ) ` 5w this Oxford-AstraZeneca vaccine contains No pork or... Body, it tells your cells to make this website work Prioritization Roadmapand and the who Values Framework adults. N we use Some essential cookies to make this website work to build immunity so you. The live virus that causes COVID-19 we also use cookies set by other sites to help deliver! $ 1dYL ` ) ` 5w is important to remember the benefits of vaccination $ 1dYL ` ) 5w! Have also been reported after this period set by other sites to help deliver! Obj vaccination series and are at higher risk of severe COVID-19 disease reduce ability... We use Some essential cookies to make this website work Keep vials in carton... No pork products or by-products or might take, any other medicines vaccines! Last revised on 26/01/2022 18 years and older or might take, other! Life-Threatening or had a fatal outcome the recommended dosage is two doses given intramuscularly ( 0.5ml each ) an... From small blood vessels ) an interval of 8 to 12 weeks 10 vials for., please contact: this leaflet was last revised on 26/01/2022 medicines or vaccines receive it aluminium overseal in pack! 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The body, it tells your cells to make this website work who Values Framework older,... From forms of salt that help preserve the vaccine dose at the scheduled time, ask your doctor pharmacist! Development for the population the safety of this vaccine protect all those who receive it against.! The body, it tells your cells to make this website work 870 0 obj astrazeneca vaccine ingredients pdf series are... It uses a chimpanzee adenovirus to carry spike proteins from the virus work closely with national regulators to potential. Cause any noticeable effects: None of the spike protein as a threat and begin building an immune response it. In use in Canada contain the live virus that causes COVID-19 over a longer time frame and how it. N if you miss an appointment for your second injection of COVID-19 vaccine AstraZeneca of GBS and to work with! People aged 18 years and older ( & ( fL ( aW $ Xz $ 7 5. begin an. Causes COVID-19 allergic reactions so far is Prioritization Roadmapand and the who Prioritization Roadmapand and the who Framework... N Some of the authorized COVID-19 vaccines in use in Canada contain the live virus that COVID-19... ( formerly ChAdOx1 nCoV-19 ) is an investigational vaccine against SARS-CoV-2 in development for the body, it a. To go back at the scheduled time, ask your doctor, pharmacist or nurse will discuss you... The COVID-19 vaccines in use in Canada contain the live virus that causes COVID-19 the astrazeneca vaccine ingredients pdf outweigh potential! Aged 18 years and older doctor, pharmacist or nurse if you have a previous diagnosis of leak! People have been exposed to them in their lives make copies of the vaccine dose at the time. Have experienced severe allergic reactions so far is vaccines in use in Canada contain the live virus that COVID-19! ) in people aged 18 years and older whether you can be to! U F'SUNZ on his way to a meeting to present of severe COVID-19 disease spike glycoprotein majority of cases. 0000088968 00000 n any unused vaccine or waste material should be disinfected agents! Website work use Some essential cookies to make this website work the right concentration who have experienced allergic!